RAF Typhoon FGR4s have conducted a mission with France's air force in a combined operation against an hidden munitions depot in Syrian territory employed by the Daesh militant organization, according to the UK's MoD.
The facility, located using reconnaissance, was believed to be housing weapons and explosive materials, the announcement noted, and was located in hills just north of the historic site of Palmyra in the heart of Syria.
"Our fighter planes employed laser-guided Paveway IV weapons to strike a several access tunnels leading to the depot... early reports indicate the objective was successfully hit," officials stated.
There was no evidence of any civilian impact in the attack conducted Saturday night and every plane involved returned safely, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager refuelling tanker.
IS - alternatively referred to as ISIS - enforced extremist governance over large swathes of both Syria and Iraq before its territorial defeat in 2019.
"This strike underscores our UK leadership, and commitment to work closely with our partners, to eradicate any resurgence of IS and their harmful and extremist ideologies in the region," the British Defence Secretary John Healey remarked.
British military aircraft have carried out surveillance missions over Syrian airspace to "deter any attempted resurgence" of IS subsequent to its defeat at the battle of Baghuz in 2019, the ministry said.
"I must thank the personnel of British forces involved in this strike for their skill and their courage," Healey added. "Including them were numerous British troops stationed over the holidays. This action, to remove militants who pose a risk to our security, shows how UK forces are ready to step up, all year round, protecting the UK domestically and influential overseas."
Last December, the American forces conducted what it described as a "large-scale strike" on IS targets in the country, after an attack claimed the lives of two US troops and a civilian interpreter in Palmyra.
The United Nations reports Daesh still has roughly 5-7 thousand combatants in Syria and Iraq.